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Our Solution
Amazon
Biotech’s HIV/AIDS Drugs
AMZ0026 family
AMZ0026 |
AMZ0026-H |
| An 11 natural plant pharmaceutical
drug |
Sister formulation |
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Greater anti-viral
activity |
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12-plant natural
pharmaceutical drug |
Advantages of
AMZ0026
ADVANTAGE |
COMMENT |
Safe |
Minimal side effects due to the low doses of the active compounds found in whole plants, acting synergistically against the disease
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Tolerable |
For
the 20% of patients who do not respond to HAART or cannot tolerate the drugs
that make up HAART regimens |
Lower Cost |
Expand market
in low- and middle-income countries |
Whole Plant Medicine |
Attractive to
"natural supplements" marketplace |
Minimize Virus Mutation |
Antivirals
increase resistant viral isolates. AMZ-0026 attacks the virus in multiple
sites thus reducing the virus’s chance to mutate |
Ease of Use |
Comes in
convenient capsules, not an injected drug |
Prior Results
Avg. %
change in absolute CD4 values following treatment with AMZ0026
Avg. %
change in CD4% following treatment
with AMZ0026
Avg. CD4/CD8 ratios at
different time points following treatment with AMZ0026
Avg. change in body
weight at different time points following treatment with
AMZ0026
Currently planned trials
Amazon is beginning a Phase I/II study to test the safety and efficacy of its Botanical Drug
Product AMZ0026 in pre-symptomatic HIV-positive patients undergoing no other
anti-retroviral therapies.
Study Design: Phase I/II, six month, double-blind, randomized, placebo-controlled study
Planned Sample Size: 32 subjects (16 / treatment arm)
Objectives/Outcomes: To
evaluate whether AMZ0026 in subjects with WHO stage I HIV, is safe, tolerable
and can result in the primary outcome of increased CD4 counts, and secondary outcomes of decreased viral loads, increased CD4/CD8 ratios
and enduring efficacy upon post-treatment follow-up relative to placebo.
AMZ0026
Future
Applications of AMZ0026
• AMZ0026 can potentially be used to treat Lyme disease.
• AMZ0026 can be potentially used to boost the immune
system on patients receiving chemotherapy.
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